Nortin 10mg Capsule 10pcs

✔️ Uses of Nortin 10mg Capsule

Treats and relieves the symptoms of depression

✔️ Side Effects of Nortin 10mg Capsule

• Hypotension, hypertension, tachycardia, MI, arrhythmias, stroke.
• Confusional states, hallucinations, anxiety, restlessness, agitation.
• Insomnia, nightmares, peripheral neuropathy, seizures.
• Dry mouth, blurred vision, constipation, urinary retention.
• Nausea, vomiting, anorexia, abdominal cramps.
• Drowsiness, dizziness, weakness, fatigue, headache.
• Sweating, flushing, gynecomastia, altered libido, weight changes.

✔️ How does Nortin 10mg Capsule work?

Nortriptyline, as a tricyclic antidepressant, works by blocking the reuptake of neurotransmitters, specifically serotonin and norepinephrine, in the central nervous system (CNS). The increased synaptic concentration of these neurotransmitters helps in regulating mood and is associated with the antidepressant effects of the medication. It is important in the treatment of conditions like depression, bed-wetting, and neuropathic pain.

✔️ Quick Suggestions:

• Take primarily at night due to potential drowsiness.
• Regular blood tests may be required.
• Inform your doctor of behavioral changes, mood changes, and suicidal thoughts.
• Avoid activities requiring concentration until the effects are known.
• Do not stop suddenly; withdrawal symptoms may occur.
• Avoid alcohol consumption as it may interact negatively.

✔️ Indication:

Nortin 10 is a tricyclic antidepressant used to treat depression, nocturnal enuresis (bedwetting), and neuropathic pain. It increases the levels of certain chemical messengers in the brain, stabilizing and enhancing mood.

✔️ Pharmacology

Nortriptyline, the active metabolite, increases synaptic concentration of serotonin and/or norepinephrine by blocking their reuptake in the CNS.

✔️ Dosage & Administration of Nortin 10mg Capsule

• Depression: Adult: 75-100 mg/day in divided doses. Max: 150 mg/day in severe depression. Elderly: 30-50 mg/day.
• Bed-wetting (Nocturnal Enuresis): Child: 6-7 yr (20-25 kg): 10 mg; 8-11 yr (25-35kg): 10-20 mg; >11 yr (35-54 kg): 25-35 mg.

✔️ Interaction

• Risk of serotonin syndrome with SSRIs, SNRIs, TCAs, triptans, fentanyl, and lithium.
• May reduce the antihypertensive effect of certain medications.
• Increased metabolism with barbiturates.
• Increased risk of arrhythmias and hypotension with anesthesia.
• Increased plasma level with fluoxetine.
• Potentially fatal interactions with MAOIs, linezolid, methylene blue.

✔️ Contraindications

Mania, recent MI, arrhythmias, severe liver disease, children <6 yr.

✔️ Pregnancy & Lactation

The security of nortriptyline for utilization in pregnancy has not been set up. Nortilin ought to as it were be given amid pregnancy when there are no choices and advantage exceeds chance.

✔️ Precautions & Warnings

• Not for bipolar depression.
• Avoid abrupt withdrawal.
• Caution in patients at risk of seizures, with diabetes, narrow-angle glaucoma, urinary retention, prostatic hyperplasia, chronic constipation, history of CV disease.
• Monitor closely for clinical changes.

✔️ Storage Conditions

Store at 15-30° C. Secure from light and dampness.